The MHRA guidance states Valproate must not be used in women of childbearing age unless a 'Pregnancy Prevention Program' is in place.  The 'Ardens Valproate Pregnancy' searches will help you to identify those patients who may need to be reviewed, to ensure they are fully informed of the risks and of the need to avoid exposure to Valproate medicines in pregnancy.


To locate these searches, navigate to the Population Reporting module > Ardens Searches > 1.4 Ardens Clinical Safety Searches > Medication Related Searches > Valproate pregnancy folder:



The first search Currently Pregnant will display all patients currently pregnant, along with a sub search which will include the pregnant patients that have been prescribed Sodium Valproate in the last 4 months. 


The second search Valproate I All patients currently issued will display all registered regular patients currently on Sodium Valproate. A further sub search is available to identify those patients of child bearing age, with no review in the last 1 year or they are currently pregnant. 


To view the results of the searches, right click on the Valproate pregnancy search folder and select Run. Patients that meet the criteria of the search, will display in the Population Included tab.


Please note -the following Ardens alert will remind you of the MHRA guidance when prescribing Valproate to a women of child - bearing age in the patient record: 



This is triggered when issuing Valproate medicines and gives the option to run our Valproate clinical template:




If you require any further assistance on the process above, please contact Ardens support on: support-emis@ardens.org.uk